Big adventures born from the colorful imaginations of babies Tommy, Chuckie, Phil, Lil, Susie and Angelica.
Tommy leads the babies on a daring adventure to help Chuckie after Chuckie's big attempt to be brave goes horribly wrong.
When a professional organizer comes over, its up to Tommy and his friends to stop her from taking all the toys; when Tommy's parents bring home a foster puppy, Tommy finds a way to keep Spike from being replaced.
Tommy's dad invents a robot dog that is allergy-free for Chuckie and Chas, but not necessarily problem-free; Angelica uses an argument between the twins to trick Phil into becoming her personal assistant.
Angelica takes advantage of a family problem to make Tommy and Chuckie play a game of house; Tommy and the babies help Chuckie take care of what he thinks is the last balloon in the whole wide world.
When Grandpa's hurt back keeps him from his favorite event, Tommy enlists his friends to create the event at home; Angelica's new talking doll is a shock to her and a surprise to the babies.
Angelica needs the babies' help adjusting to life without her Cynthia car when her car privileges are taken away; Tommy and his friends must keep Angelica under control when she discovers a way to get any toy she asks for.